Path of Exile 2: I Want to Run a Program Which Fixes Stutters in Games but Poe 2 Has… (Workarounds)
Short answer
Suggested fix (unconfirmed): Use Lossless Scaling to run the game without triggering the anti-cheat. Alternatively, switch to the Vulkan API to eliminate stutters.
Suggested fix (unconfirmed): Rerun the map with a new one. If the glowing green fissure near the boss area fails to close again, clear the map entirely to ensure all mobs are defeated.
Suggested fix (unconfirmed): Reset the minion count by reducing it to zero with the minus button, then increase it back to your maximum amount. If that fails, toggle your weapon set or check if attached skill gems increased the spirit cost beyond your available pool.