Were Achievements Bugged?
Suggested fix (unconfirmed): Restart the game or check your internet connection, as achievements may be delayed.

4 fixes · 12 how-to answers · Steam discussions
Suggested fix (unconfirmed): Restart the game or check your internet connection, as achievements may be delayed.
Suggested fix (unconfirmed): Play the game in windowed mode instead of fullscreen. If the issue persists, update or reinstall your GPU drivers.
No confirmed fix yet. Players suggest: in general crashing shouldn't delete your save at all...
Yes, that worked fine. Just couldn't transfer without opening the bags inventory.
Suggested fix (unconfirmed): Play on a lower difficulty or customize the game modifiers to your liking to finish a run more easily.
SPOILERS!!!
Multiplayer Mod
Suggested fix (unconfirmed): Hold a mini-barrel in your main hand and type `addliquid [type] [amount]` in the console. For example, enter `addliquid fentanyl 10000`.
Suggested fix (unconfirmed): Play on an easier setting and survive all the layers. Alternatively, use the command "skiplayer 9" to reach the end quickly.
No confirmed fix yet. Players suggest: Unless of course you set the loot modifier to some ♥♥♥♥ like 25%.
Suggested fix (unconfirmed): Break the bricks to escape the spawn room since you lack human blood for the door terminal.
Suggested fix (unconfirmed): Type `Saveandquit` into the console to return to the menu, then overwrite your save with a new run. Alternatively, use Alt-F4 to wipe your save immediately upon dying.
Suggested fix (unconfirmed): Memorize the recipes until they become second nature, or install crafting priority mods. Put materials in your hands before crafting to prioritize them.
For fellow experiments down there
Overwhelmed by the crafting menu? Don't know where to even begin using your BEST ingame ability? This should help. c:
Suggested fix (unconfirmed): Play on the Paradise difficulty setting using custom options with an increased timer and loot. Move slowly, learn the items, traps, and crafting recipes, and use the 'T' key to throw items for a recoil boost to avoid traps.